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Encapsulation of a nanoporous simvastatin-chitosan composite to enhance osteointegration of hydroxyapatite-coated polyethylene terephthalate ligaments

PURPOSE: This study was designed to evaluate the in vitro and in vivo biocompatibility and osteointegration of plasma-sprayed hydroxyapatite (HA)-coated polyethylene terephthalate (PET) ligaments encapsulated with a simvastatin (SV)-chitosan (CS) composite. METHODS: This study compared the in vitro...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Ding, Xiaoquan, Wang, Siheng, Jin, Wenhe, Liu, Xingwang, Chen, Jun, Chen, Shiyi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613541/
https://ncbi.nlm.nih.gov/pubmed/31308664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S210687
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