Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury

Liver ischemia and reperfusion injury (IRI) is a major challenge in liver surgery. Diet restriction reduces liver damage by increasing stress resistance; however, the underlying molecular mechanisms remain unclear. We investigated the preventive effect of 12-h fasting on mouse liver IRI. Partial war...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Miyauchi, Tomoyuki, Uchida, Yoichiro, Kadono, Kentaro, Hirao, Hirofumi, Kawasoe, Junya, Watanabe, Takeshi, Ueda, Shugo, Okajima, Hideaki, Terajima, Hiroaki, Uemoto, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613133/
https://ncbi.nlm.nih.gov/pubmed/31196960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820282116
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