Circuit-specific control of the medial entorhinal inputs to the dentate gyrus by atypical presynaptic NMDARs activated by astrocytes

Here, we investigated the properties of presynaptic N-methyl-d-aspartate receptors (pre-NMDARs) at corticohippocampal excitatory connections between perforant path (PP) afferents and dentate granule cells (GCs), a circuit involved in memory encoding and centrally affected in Alzheimer’s disease and...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Savtchouk, Iaroslav, Di Castro, Maria Amalia, Ali, Rugina, Stubbe, Hiltrud, Luján, Rafael, Volterra, Andrea
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612919/
https://ncbi.nlm.nih.gov/pubmed/31152131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816013116
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