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PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors

MOTIVATION: Cell lines and patient-derived xenografts (PDXs) have been used extensively to understand the molecular underpinnings of cancer. While core biological processes are typically conserved, these models also show important differences compared to human tumors, hampering the translation of fi...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Mourragui, Soufiane, Loog, Marco, van de Wiel, Mark A, Reinders, Marcel J T, Wessels, Lodewyk F A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612899/
https://ncbi.nlm.nih.gov/pubmed/31510654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz372
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