Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Cellular senescence is triggered by diverse stimuli and is characterized by long‐term growth arrest and secretion of cytokines and chemokines (termed the SASP—senescence‐associated secretory phenotype). Senescence can be organismally beneficial as it can prevent the propagation of damaged or mutated...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Pantazi, Asimina, Quintanilla, Andrea, Hari, Priya, Tarrats, Nuria, Parasyraki, Eleftheria, Dix, Flora L., Patel, Jaiyogesh, Chandra, Tamir, Acosta, Juan Carlos, Finch, Andrew J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612703/
https://ncbi.nlm.nih.gov/pubmed/31148378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12981
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