Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Cellular senescence is triggered by diverse stimuli and is characterized by long‐term growth arrest and secretion of cytokines and chemokines (termed the SASP—senescence‐associated secretory phenotype). Senescence can be organismally beneficial as it can prevent the propagation of damaged or mutated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Pantazi, Asimina, Quintanilla, Andrea, Hari, Priya, Tarrats, Nuria, Parasyraki, Eleftheria, Dix, Flora L., Patel, Jaiyogesh, Chandra, Tamir, Acosta, Juan Carlos, Finch, Andrew J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612703/
https://ncbi.nlm.nih.gov/pubmed/31148378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12981
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