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Galectin-3 is Essential for IgE-Dependent Activation of Human Basophils by A549 Lung Epithelial Cells

Using novel co-culture model systems, galectin-3 is shown to facilitate basophil secretion of IL-4/IL-13, with implications that this unique mode of activation may be linked to a variety of diseases ranging from asthma to cancer.

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Schroeder, John T., Adeosun, Abiodun A., Do, Danh, Bieneman, Anja P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612293/
https://ncbi.nlm.nih.gov/pubmed/30857982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.03.001
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