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IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells

BACKGROUND: Natural killer (NK) cells are an emerging new tool for cancer immunotherapy. To develop NK cell therapeutics from peripheral blood mononuclear cells (PBMCs) of healthy donors, substantial expansion of primary NK cells is necessary because of the very low number of these cells in peripher...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Choi, Yeon Ho, Lim, Eun Jin, Kim, Se Wha, Moon, Yong Wha, Park, Kyung Soon, An, Hee-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612093/
https://ncbi.nlm.nih.gov/pubmed/31277710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0652-7
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