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Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7
In the central nervous system (CNS), oligodendrocytes myelinate multiple axons; in the peripheral nervous system (PNS), Schwann cells (SCs) myelinate a single axon. Why are the myelinating potentials of these glia so fundamentally different? Here, we find that loss of Fbxw7, an E3 ubiquitin ligase c...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6611888/ https://ncbi.nlm.nih.gov/pubmed/31278268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10881-y |
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