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Iron overload reduces synthesis and elimination of bile acids in rat liver

Excessive iron accumulation in the liver, which accompanies certain genetic or metabolic diseases, impairs bile acids (BA) synthesis, but the influence of iron on the complex process of BA homeostasis is unknown. Thus, we evaluated the effect of iron overload (IO) on BA turnover in rats. Compared wi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Prasnicka, Alena, Lastuvkova, Hana, Alaei Faradonbeh, Fatemeh, Cermanova, Jolana, Hroch, Milos, Mokry, Jaroslav, Dolezelova, Eva, Pavek, Petr, Zizalova, Katerina, Vitek, Libor, Nachtigal, Petr, Micuda, Stanislav
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611795/
https://ncbi.nlm.nih.gov/pubmed/31278332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46150-7
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