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Optimizing the alignment of thermoresponsive poly(N-isopropyl acrylamide) electrospun nanofibers for tissue engineering applications: A factorial design of experiments approach

Thermoresponsive polymers, such as poly(N-isopropyl acrylamide) (PNIPAM), have been identified and used as cell culture substrates, taking advantage of the polymer’s lower critical solution temperature (LCST) to mechanically harvest cells. This technology bypasses the use of biochemical enzymes that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Young, Rachel E., Graf, Jodi, Miserocchi, Isabella, Van Horn, Ryan M., Gordon, Melissa B., Anderson, Christopher R., Sefcik, Lauren S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611625/
https://ncbi.nlm.nih.gov/pubmed/31276542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219254
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