Optimizing the alignment of thermoresponsive poly(N-isopropyl acrylamide) electrospun nanofibers for tissue engineering applications: A factorial design of experiments approach

Thermoresponsive polymers, such as poly(N-isopropyl acrylamide) (PNIPAM), have been identified and used as cell culture substrates, taking advantage of the polymer’s lower critical solution temperature (LCST) to mechanically harvest cells. This technology bypasses the use of biochemical enzymes that...

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發表在:PLoS One
Main Authors: Young, Rachel E., Graf, Jodi, Miserocchi, Isabella, Van Horn, Ryan M., Gordon, Melissa B., Anderson, Christopher R., Sefcik, Lauren S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611625/
https://ncbi.nlm.nih.gov/pubmed/31276542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219254
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