Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin

Despite its poor bioavailability, curcumin is a promising natural polyphenol targeting NF-κβ. NF-κβ is a target for new therapeutics because it plays a pivotal role in the pathophysiology of Alzheimer disease (AD). In contrast, ambrsoin, a sesquiterpene lactone which is a potent NF-κβ inhibitor, is...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Khalil, Mohammed N. A., Choucry, Mouchira A., El Senousy, Amira S., Hassan, Azza, El-Marasy, Salma A., El Awdan, Sally A., Omar, Farghaly A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611615/
https://ncbi.nlm.nih.gov/pubmed/31276550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219378
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