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PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix

Cisplatin is a keystone for treatment of both recurring and locally advanced cervical cancer. However toxic side effects and acquired resistance limits its efficacy. Enhanced DNA repair is one of the mechanisms through which cancer cells acquire cisplatin resistance. Inhibitors of PARP, which is a D...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Mann, Minakshi, Kumar, Sachin, Sharma, Ashok, Chauhan, Shyam S., Bhatla, Neerja, Kumar, Sunesh, Bakhshi, Sameer, Gupta, Ritu, Kumar, Lalit
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611509/
https://ncbi.nlm.nih.gov/pubmed/31303961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27008
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