Could AGE/RAGE-Related Oxidative Homeostasis Dysregulation Enhance Susceptibility to Pathogenesis of Cardio-Metabolic Complications in Childhood Obesity?

Background: Advanced glycation end-products (AGEs) and their cell receptor (RAGE) are involved in the pathophysiology of cardio-metabolic diseases. Interaction of AGEs with RAGE results in increased generation of oxygen radicals and pro-inflammatory cytokines. Circulating soluble RAGE (sRAGE) intera...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Corica, Domenico, Aversa, Tommaso, Ruggeri, Rosaria Maddalena, Cristani, Mariateresa, Alibrandi, Angela, Pepe, Giorgia, De Luca, Filippo, Wasniewska, Malgorzata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611173/
https://ncbi.nlm.nih.gov/pubmed/31316471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00426
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