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Pharmacokinetic analysis of new synthetic antimalarial N-251

BACKGROUND: With the emergence and growing number of drug-resistant Plasmodium falciparum, a new drug for malaria control must be urgently developed. The new antimalarial synthetic compound N-251 was recently discovered. As an endoperoxide structure in the body, the compound shows high antimalarial...

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Publicado en:Trop Med Health
Main Authors: Okada, Kazuaki, Sato, Akira, Hiramoto, Akiko, Isogawa, Rena, Kurosaki, Yuji, Higaki, Kazutaka, Miyoshi, Shin-Ichi, Chang, Kyung-Soo, Kim, Hye-Sook
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611044/
https://ncbi.nlm.nih.gov/pubmed/31312098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41182-019-0167-4
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