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Determining cell-type abundance and expression from bulk tissues with digital cytometry

Single-cell RNA-seq (scRNA-seq) has emerged as a powerful technique for characterizing cellular heterogeneity, but it is currently impractical on large sample cohorts and cannot be applied to fixed specimens collected as part of routine clinical care. We previously developed an approach for digital...

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發表在:Nat Biotechnol
Main Authors: Newman, Aaron M., Steen, Chloé B., Liu, Chih Long, Gentles, Andrew J., Chaudhuri, Aadel A., Scherer, Florian, Khodadoust, Michael S., Esfahani, Mohammad S., Luca, Bogdan A., Steiner, David, Diehn, Maximilian, Alizadeh, Ash A.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610714/
https://ncbi.nlm.nih.gov/pubmed/31061481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0114-2
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