miR-340-5p Suppresses Aggressiveness in Glioblastoma Multiforme by Targeting Bcl-w and Sox2

Glioblastoma multiforme (GBM), a particularly aggressive type of malignant brain tumor, has a high mortality rate. Bcl-w, an oncogene, is reported to enhance cell survival, proliferation, epithelial-mesenchymal transition (EMT), migratory and invasive abilities, and stemness maintenance in a variety...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Kim, Sanghwa, Choi, Jae Yeon, Seok, Hyun Jeong, Park, Myung-Jin, Chung, Hee Yong, Bae, In Hwa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610659/
https://ncbi.nlm.nih.gov/pubmed/31272074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.05.022
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