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Cyclophosphamide Regulates N6-Methyladenosine and m6A RNA Enzyme Levels in Human Granulosa Cells and in Ovaries of a Premature Ovarian Aging Mouse Model

Cyclophosphamide (CTX) is one of the most frequently used alkylating anticancer drugs. CTX is associated with reproductive failure and premature ovarian insufficiency (POI) or premature ovarian aging. Much less is known about the mechanism by which CTX affects female fertility through N6-methyladeno...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Huang, Boxian, Ding, Chenyue, Zou, Qinyan, Wang, Wei, Li, Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610338/
https://ncbi.nlm.nih.gov/pubmed/31316467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00415
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