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The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs

Up to date, preclinical screening for new antiepileptic substances is performed by a combination of different in vivo models of acute seizures, for which large numbers of animals are necessary. So far, little attention has been paid to in vitro models, which are also able to detect antiepileptic eff...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Heuzeroth, Hanno, Wawra, Matthias, Fidzinski, Pawel, Dag, Ramazan, Holtkamp, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610309/
https://ncbi.nlm.nih.gov/pubmed/31316344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00677
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