Genome-wide DNA methylation profile of early-onset endometrial cancer: its correlation with genetic aberrations and comparison with late-onset endometrial cancer

The present study was performed to clarify the significance of DNA methylation alterations during endometrial carcinogenesis. Genome-wide DNA methylation analysis and targeted sequencing of tumor-related genes were performed using the Infinium MethylationEPIC BeadChip and the Ion AmpliSeq Cancer Hot...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Makabe, Takeshi, Arai, Eri, Hirano, Takuro, Ito, Nanako, Fukamachi, Yukihiro, Takahashi, Yoriko, Hirasawa, Akira, Yamagami, Wataru, Susumu, Nobuyuki, Aoki, Daisuke, Kanai, Yae
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Biology, Genetics and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610171/
https://ncbi.nlm.nih.gov/pubmed/30850842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz046
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