Trisomy 21 Is a Cause of Permanent Neonatal Diabetes That Is Autoimmune but Not HLA Associated

Identifying new causes of permanent neonatal diabetes (PNDM) (diagnosis <6 months) provides important insights into β-cell biology. Patients with Down syndrome (DS) resulting from trisomy 21 are four times more likely to have childhood diabetes with an intermediate HLA association. It is not know...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Johnson, Matthew B., De Franco, Elisa, Greeley, Siri Atma W., Letourneau, Lisa R., Gillespie, Kathleen M., Wakeling, Matthew N., Ellard, Sian, Flanagan, Sarah E., Patel, Kashyap A., Hattersley, Andrew T.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2019
Fag:
Genetics/Genomes/Proteomics/Metabolomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609990/
https://ncbi.nlm.nih.gov/pubmed/30962220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0045
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