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Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation

The tumor suppressor activity of maspin (mammary serine protease inhibitor) has been associated with its nuclear localization. In this study we explore the regulation of maspin nuclear translocation. An in vitro nuclear import assay suggested that maspin can passively enter the nucleus. However, in ...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Reina, Jeffrey, Zhou, Lixin, Fontes, Marcos R. M., Panté, Nelly, Cella, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609763/
https://ncbi.nlm.nih.gov/pubmed/31144423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12626
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