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The β‐domain of streptokinase affects several functionalities, including specific/proteolytic activity kinetics
Streptokinase (SK) is a plasminogen activator which converts inactive plasminogen (Pg) to active plasmin (Pm), which cleaves fibrin clots. SK secreted by groups A, C, and G Streptococcus (SKA/SKC/SKG) is composed of three domains: SKα, SKβ and SKγ. Previous domain‐swapping studies between SK1/SK2b‐c...
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Publicado no: | FEBS Open Bio |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609762/ https://ncbi.nlm.nih.gov/pubmed/31087538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12657 |
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