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Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Hundreds of cellular host factors are required to support dengue virus infection, but their identity and roles are incompletely characterized. Here, we identify human host dependency factors required for efficient dengue virus-2 (DENV2) infection of human cells. We focused on two, TTC35 and TMEM111,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barrows, Nicholas J., Anglero-Rodriguez, Yesseinia, Kim, Byungil, Jamison, Sharon F., Le Sommer, Caroline, McGee, Charles E., Pearson, James L., Dimopoulos, George, Ascano, Manuel, Bradrick, Shelton S., Garcia-Blanco, Mariano A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609633/
https://ncbi.nlm.nih.gov/pubmed/31273220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45910-9
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