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Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Hundreds of cellular host factors are required to support dengue virus infection, but their identity and roles are incompletely characterized. Here, we identify human host dependency factors required for efficient dengue virus-2 (DENV2) infection of human cells. We focused on two, TTC35 and TMEM111,...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Barrows, Nicholas J., Anglero-Rodriguez, Yesseinia, Kim, Byungil, Jamison, Sharon F., Le Sommer, Caroline, McGee, Charles E., Pearson, James L., Dimopoulos, George, Ascano, Manuel, Bradrick, Shelton S., Garcia-Blanco, Mariano A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609633/
https://ncbi.nlm.nih.gov/pubmed/31273220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45910-9
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