Strain‐selective efficacy of sacubitril/valsartan on carotid fibrosis in response to injury in two inbred mouse strains

BACKGROUND AND PURPOSE: Sacubitril/valsartan (Sac/val) is more effective than valsartan in lowering BP and mortality in patients with heart failure. Here, we proposed that Sac/val treatment would be more effective in preventing pathological vascular remodelling in 129X1/SvJ (129X1), than in C57BL/6J...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Korshunov, Vyacheslav A., Quinn, Breandan, Faiyaz, Abrar, Ahmed, Rifat, Sowden, Mark P., Doyley, Marvin M., Berk, Bradford C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609549/
https://ncbi.nlm.nih.gov/pubmed/31077344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14708
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