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Negative Events During Adulthood are Associated With Symptom Severity and Altered Stress Response in Patients With Irritable Bowel Syndrome

BACKGROUND & AIMS: Irritable bowel syndrome (IBS) is a stress-sensitive disorder associated with dysregulation of the hypothalamic–pituitary–adrenal pathway. We studied the cumulative effect of events during adulthood on this pathway in patients with IBS. METHODS: We studied 129 patients with IB...

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Detalhes bibliográficos
Publicado no:Clin Gastroenterol Hepatol
Main Authors: Parker, Colleen H., Naliboff, Bruce D., Shih, Wendy, Presson, Angela P., Videlock, Elizabeth J., Mayer, Emeran A., Lin, Chang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609507/
https://ncbi.nlm.nih.gov/pubmed/30616026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2018.12.029
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