Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens

Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P[8] genotype accounting for more than 80% of infections in humans. The molecular bases for binding of the VP8* domain from P[8] VP4 spike protein to its cellular receptor, the secretory H type-1 antigen (Fuc-α1...

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Udgivet i:PLoS Pathog
Main Authors: Gozalbo-Rovira, Roberto, Ciges-Tomas, J. Rafael, Vila-Vicent, Susana, Buesa, Javier, Santiso-Bellón, Cristina, Monedero, Vicente, Yebra, María J., Marina, Alberto, Rodríguez-Díaz, Jesús
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609034/
https://ncbi.nlm.nih.gov/pubmed/31226167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007865
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