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Actin clearance promotes polarized dynein accumulation at the immunological synapse

Immunological synapse (IS) formation between a T cell and an antigen-presenting cell is accompanied by the reorientation of the T cell centrosome toward the interface. This polarization response is thought to enhance the specificity of T cell effector function by enabling the directional secretion o...

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Pubblicato in:PLoS One
Autori principali: Sanchez, Elisa, Liu, Xin, Huse, Morgan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608937/
https://ncbi.nlm.nih.gov/pubmed/31269031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210377
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