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Cholesterol Functionalization of Gold Nanoparticles Enhances Photoactivation of Neural Activity

Gold nanoparticles (AuNPs) attached to the extracellular leaflet of the plasma membrane of neurons can enable the generation of action potentials (APs) in response to brief pulses of light. Recently described techniques to stably bind AuNP bioconjugates directly to membrane proteins (ion channels) i...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Carvalho-de-Souza, Joao L., Nag, Okhil K., Oh, Eunkeu, Huston, Alan L., Vurgaftman, Igor, Pepperberg, David R., Bezanilla, Francisco, Delehanty, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608567/
https://ncbi.nlm.nih.gov/pubmed/30589551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00486
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