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RAS/ERK Signaling Controls Proneural Genetic Programs in Cortical Development and Gliomagenesis

Neural cell fate specification is well understood in the embryonic cerebral cortex, where the proneural genes Neurog2 and Ascl1 are key cell fate determinants. What is less well understood is how cellular diversity is generated in brain tumors. Gliomas and glioneuronal tumors, which are often locali...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Li, Saiqun, Mattar, Pierre, Dixit, Rajiv, Lawn, Samuel O., Wilkinson, Grey, Kinch, Cassandra, Eisenstat, David, Kurrasch, Deborah M., Chan, Jennifer A., Schuurmans, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608536/
https://ncbi.nlm.nih.gov/pubmed/24501358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4077-13.2014
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