Acute and Sustained Effects of Methylphenidate on Cognition and Presynaptic Dopamine Metabolism: An [(18)F]FDOPA PET Study

Methylphenidate (MPH) inhibits the reuptake of dopamine and noradrenaline. PET studies with MPH challenge show increased competition at postsynaptic D(2/3)-receptors, thus indirectly revealing presynaptic dopamine release. We used [(18)F]fluorodopamine ([(18)F]FDOPA)-PET in conjunction with the inle...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schabram, Ina, Henkel, Karsten, Shali, Siamak Mohammadkhani, Dietrich, Claudia, Schmaljohann, Jörn, Winz, Oliver, Prinz, Susanne, Rademacher, Lena, Neumaier, Bernd, Felzen, Marc, Kumakura, Yoshitaka, Cumming, Paul, Mottaghy, Felix M., Gründer, Gerhard, Vernaleken, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608425/
https://ncbi.nlm.nih.gov/pubmed/25355228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1560-14.2014
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