Endogenous Opioid-Induced Neuroplasticity of Dopaminergic Neurons in the Ventral Tegmental Area Influences Natural and Opiate Reward

Natural reward and drugs of abuse converge on the mesolimbic pathway and activate common mechanism of neural plasticity in the nucleus accumbens. Chronic exposure to opiates induces plasticity in dopaminergic neurons of the ventral tegmental area (VTA), which regulates morphine reward tolerance. Her...

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Vydáno v:J Neurosci
Hlavní autoři: Pitchers, Kyle K., Coppens, Caroline M., Beloate, Lauren N., Fuller, Jonathan, Van, Sandy, Frohmader, Karla S., Laviolette, Steven R., Lehman, Michael N., Coolen, Lique M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608201/
https://ncbi.nlm.nih.gov/pubmed/24966382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0133-14.2014
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