Endogenous Opioid-Induced Neuroplasticity of Dopaminergic Neurons in the Ventral Tegmental Area Influences Natural and Opiate Reward

Natural reward and drugs of abuse converge on the mesolimbic pathway and activate common mechanism of neural plasticity in the nucleus accumbens. Chronic exposure to opiates induces plasticity in dopaminergic neurons of the ventral tegmental area (VTA), which regulates morphine reward tolerance. Her...

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Publicado no:J Neurosci
Main Authors: Pitchers, Kyle K., Coppens, Caroline M., Beloate, Lauren N., Fuller, Jonathan, Van, Sandy, Frohmader, Karla S., Laviolette, Steven R., Lehman, Michael N., Coolen, Lique M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608201/
https://ncbi.nlm.nih.gov/pubmed/24966382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0133-14.2014
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