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Reversal of apoE4-Driven Brain Pathology and Behavioral Deficits by Bexarotene

Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for Alzheimer's disease (AD), is less lipidated than its corresponding AD-benign form, apoE3, and it has been suggested that the pathological effects of apoE4 are mediated by lipid-related mechanisms. ATP-binding cassette transpo...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Boehm-Cagan, Anat, Michaelson, Daniel M.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608187/
https://ncbi.nlm.nih.gov/pubmed/24849361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5198-13.2014
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