IRF2BP2 transcriptional repressor restrains naive CD4 T cell activation and clonal expansion induced by TCR triggering

CD4 T cell activation and differentiation mechanisms constitute a complex and intricate signaling network involving several regulatory proteins. IRF2BP2 is a transcriptional repressor that is involved in gene‐expression regulation in very diverse biologic contexts. Information regarding the IRF2BP2...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Sécca, Cristiane, Faget, Douglas V., Hanschke, Steffi C., Carneiro, Mayra S., Bonamino, Martin H., de‐Araujo‐Souza, Patricia S., Viola, João P. B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Receptors, Signal Transduction, & Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608065/
https://ncbi.nlm.nih.gov/pubmed/27286791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0815-368R
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