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IL‐23 restoration of Th17 effector function is independent of IL‐6 and TGF‐β in a mouse model of alcohol and burn injury

T cells play a critical role in host defense against intestinal bacteria. We have shown that ethanol combined with burn injury suppresses Peyer's patch (PP) Th17 cytokines 1 d after injury. We assessed the mechanism of suppressed Th17 effector functions. Mice were gavaged with ethanol 4 h befor...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Li, Xiaoling, Cannon, Abigail R., Hammer, Adam M., Morris, Niya L., Choudhry, Mashkoor A.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608048/
https://ncbi.nlm.nih.gov/pubmed/28684599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1216-527R
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