Depletion of Host Cell Focal Adhesion Kinase Increases the Susceptibility to Invasion by Trypanosoma cruzi Metacyclic Forms

Focal adhesion kinase (FAK), a cytoplasmic protein tyrosine kinase (PTK), is implicated in diverse cellular processes, including the regulation of F-actin dynamics. Host cell F-actin rearrangement is critical for invasion of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. It is...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Onofre, Thiago Souza, Rodrigues, João Paulo Ferreira, Yoshida, Nobuko
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607697/
https://ncbi.nlm.nih.gov/pubmed/31297342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00231
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