Adrenomedullin in heart failure: pathophysiology and therapeutic application

Adrenomedullin (ADM) is a peptide hormone first discovered in 1993 in pheochromocytoma. It is synthesized by endothelial and vascular smooth muscle cells and diffuses freely between blood and interstitium. Excretion of ADM is stimulated by volume overload to maintain endothelial barrier function. Di...

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Detalhes bibliográficos
Publicado no:Eur J Heart Fail
Main Authors: Voors, Adriaan A., Kremer, Daan, Geven, Christopher, ter Maaten, Jozine M., Struck, Joachim, Bergmann, Andreas, Pickkers, Peter, Metra, Marco, Mebazaa, Alexandre, Düngen, Hans‐Dirk, Butler, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd. 2018
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Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607488/
https://ncbi.nlm.nih.gov/pubmed/30592365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.1366
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