Adrenomedullin in heart failure: pathophysiology and therapeutic application

Adrenomedullin (ADM) is a peptide hormone first discovered in 1993 in pheochromocytoma. It is synthesized by endothelial and vascular smooth muscle cells and diffuses freely between blood and interstitium. Excretion of ADM is stimulated by volume overload to maintain endothelial barrier function. Di...

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Détails bibliographiques
Publié dans:Eur J Heart Fail
Auteurs principaux: Voors, Adriaan A., Kremer, Daan, Geven, Christopher, ter Maaten, Jozine M., Struck, Joachim, Bergmann, Andreas, Pickkers, Peter, Metra, Marco, Mebazaa, Alexandre, Düngen, Hans‐Dirk, Butler, Javed
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd. 2018
Sujets:
Reviews
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607488/
https://ncbi.nlm.nih.gov/pubmed/30592365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.1366
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