Adrenomedullin in heart failure: pathophysiology and therapeutic application

Adrenomedullin (ADM) is a peptide hormone first discovered in 1993 in pheochromocytoma. It is synthesized by endothelial and vascular smooth muscle cells and diffuses freely between blood and interstitium. Excretion of ADM is stimulated by volume overload to maintain endothelial barrier function. Di...

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Bibliographic Details
Published in:Eur J Heart Fail
Main Authors: Voors, Adriaan A., Kremer, Daan, Geven, Christopher, ter Maaten, Jozine M., Struck, Joachim, Bergmann, Andreas, Pickkers, Peter, Metra, Marco, Mebazaa, Alexandre, Düngen, Hans‐Dirk, Butler, Javed
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607488/
https://ncbi.nlm.nih.gov/pubmed/30592365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.1366
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