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Discovery and validation of temporal patterns involved in human brain ketometabolism in cerebral microdialysis fluids of traumatic brain injury patients

BACKGROUND: Traumatic brain injury (TBI) is recognized as a metabolic disease, characterized by acute cerebral glucose hypo-metabolism. Adaptive metabolic responses to TBI involve the utilization of alternative energy substrates, such as ketone bodies. Cerebral microdialysis (CMD) has evolved as an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Eiden, Michael, Christinat, Nicolas, Chakrabarti, Anirikh, Sonnay, Sarah, Miroz, John-Paul, Cuenoud, Bernard, Oddo, Mauro, Masoodi, Mojgan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606955/
https://ncbi.nlm.nih.gov/pubmed/31202815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.05.054
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