Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon

Toxoplasma gondii evades host immunity to establish a chronic infection. Here, we assessed the role of parasitophorous vacuole (PV) membrane (PVM)- and intravacuolar network (IVN) membrane-localized dense granule (GRA) proteins in the development of acute and chronic Toxoplasma infection. Deletion o...

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Enregistré dans:
Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Fox, Barbara A., Guevara, Rebekah B., Rommereim, Leah M., Falla, Alejandra, Bellini, Valeria, Pètre, Graciane, Rak, Camille, Cantillana, Viviana, Dubremetz, Jean-François, Cesbron-Delauw, Marie-France, Taylor, Gregory A., Mercier, Corinne, Bzik, David J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606796/
https://ncbi.nlm.nih.gov/pubmed/31266861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00589-19
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