Polydatin Attenuates Neuronal Loss via Reducing Neuroinflammation and Oxidative Stress in Rat MCAO Models

Ischemic stroke is characterized by permanent or transient obstruction of blood flow, which initiates a cascading pathological process, starting from acute ATP loss and ionic imbalance to subsequent membrane depolarization, glutamate excitotoxicity, and calcium overload. These initial events are fol...

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Vydáno v:Front Pharmacol
Hlavní autoři: Shah, Fawad Ali, Kury, Lina Al, Li, Tao, Zeb, Alam, Koh, Phil Ok, Liu, Fang, Zhou, Qiang, Hussain, Ishtiaq, Khan, Arif Ullah, Jiang, Yuhua, Li, Shupeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606791/
https://ncbi.nlm.nih.gov/pubmed/31293416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00663
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