A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer

Background: We previously demonstrated that a Danshensu-Tetramethylpyrazine conjugate DT-010 enhanced anticancer effect of doxorubicin (Dox) in Dox-sensitive human breast cancer cells, and protected against Dox-induced cardiotoxicity. This work was designed to see whether DT-010 overcomes Dox resist...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Zhou, Xinhua, Wang, Anqi, Wang, Liang, Yin, Jianhua, Wang, Li, Di, Lijun, Hoi, Maggie Pui-Man, Shan, Luchen, Wu, Xu, Wang, Yuqiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606714/
https://ncbi.nlm.nih.gov/pubmed/31293428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00722
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