Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep

Preterm brain injury is highly associated with inflammation, which is likely related in part to sterile responses to hypoxia-ischemia. We have recently shown that neuroprotection with inflammatory pre-conditioning in the immature brain is associated with induction of toll-like receptor 7 (TLR7). We...

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Vydáno v:Sci Rep
Hlavní autoři: Cho, Kenta H. T., Wassink, Guido, Galinsky, Robert, Xu, Bing, Mathai, Sam, Dhillon, Simerdeep K., van den Heuij, Lotte G., Davidson, Joanne O., Weaver-Mikaere, Luke, Bennet, Laura, Gunn, Alistair J., Fraser, Mhoyra
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606639/
https://ncbi.nlm.nih.gov/pubmed/31267031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45872-y
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