Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep

Preterm brain injury is highly associated with inflammation, which is likely related in part to sterile responses to hypoxia-ischemia. We have recently shown that neuroprotection with inflammatory pre-conditioning in the immature brain is associated with induction of toll-like receptor 7 (TLR7). We...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Cho, Kenta H. T., Wassink, Guido, Galinsky, Robert, Xu, Bing, Mathai, Sam, Dhillon, Simerdeep K., van den Heuij, Lotte G., Davidson, Joanne O., Weaver-Mikaere, Luke, Bennet, Laura, Gunn, Alistair J., Fraser, Mhoyra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606639/
https://ncbi.nlm.nih.gov/pubmed/31267031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45872-y
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