Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens the way to human genetics studies, clinical trials, and precise cell atlases of large organs. However, such applications are currently limite...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gaublomme, Jellert T., Li, Bo, McCabe, Cristin, Knecht, Abigail, Yang, Yiming, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Waldman, Julia, Dionne, Danielle, Nguyen, Lan, De Jager, Philip L., Yeung, Bertrand, Zhao, Xinfang, Habib, Naomi, Rozenblatt-Rosen, Orit, Regev, Aviv
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606589/
https://ncbi.nlm.nih.gov/pubmed/31266958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10756-2
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