Alpha particle Radium 223 dichloride in high-risk osteosarcoma: a phase I dose escalation trial

PURPOSE: The prognosis of metastatic osteosarcoma continues to be poor. We hypothesized that alpha-emitting, bone-targeting radium 223 dichloride ((223)RaCl(2)) can be safely administered to patients with osteosarcoma and that early signals of response or resistance can be assessed by quantitative a...

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Publicat a:Clin Cancer Res
Autors principals: Subbiah, Vivek, Anderson, Pete M., Kairemo, Kalevi, Hess, Kenneth, Huh, Winston W., Ravi, Vinod, Daw, Najat C., Somaiah, Neeta, Ludwig, Joseph A, Benjamin, Robert S., Chawla, Sant, Hong, David S., Meric-Bernstam, Funda, Ravizzini, Gregory, Kleinerman, Eugenie, Macapinlac, Homer, Rohren, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606382/
https://ncbi.nlm.nih.gov/pubmed/30733229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3964
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