Analysis of heritability and genetic architecture of Pancreatic Cancer: A PanC4 Study

BACKGROUND: Pancreatic cancer is the fourth-leading cause of cancer death in both men and women in the United States. Identified common susceptibility loci account for a small fraction of estimated heritability. We sought to estimate overall heritability of pancreatic cancer and partition the herita...

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Publié dans:Cancer Epidemiol Biomarkers Prev
Auteurs principaux: Chen, Fei, Childs, Erica J., Mocci, Evelina, Bracci, Paige, Gallinger, Steven, Li, Donghui, Neale, Rachel E, Olson, Sara H, Scelo, Ghislaine, Bamlet, William R., Blackford, Amanda L., Borges, Michael, Brennan, Paul, Chaffee, Kari G, Duggal, Priya, Hassan, Manal J., Holly, Elizabeth A., Hung, Rayjean J, Goggins, Michael G., Kurtz, Robert C, Oberg, Ann L, Orlow, Irene, Yu, Herbert, Petersen, Gloria M, Risch, Harvey A, Klein, Alison P
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606380/
https://ncbi.nlm.nih.gov/pubmed/31015203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-18-1235
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