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Targeting the High Mobility Group Box 3 protein sensitizes chemoresistant ovarian cancer cells to cisplatin

Chemotherapeutic regimens for ovarian cancer often include the use of DNA interstrand crosslink-inducing agents (e.g. platinum drugs) or DNA double-strand break-inducing agents. Unfortunately, the majority of patients fail to maintain a durable response to treatment, in part due to drug resistance,...

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Publicat a:Cancer Res
Autors principals: Mukherjee, Anirban, Van, Huynh, Gaines, Kailee, Reh, Wade A., Vasquez, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606364/
https://ncbi.nlm.nih.gov/pubmed/31061066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0542
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