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CRISPR/Cas9-based genome editing in the era of CAR T cell immunotherapy

The advent of engineered T cells as a form of immunotherapy marks the beginning of a new era in medicine, providing a transformative way to combat complex diseases such as cancer. Following FDA approval of CAR T cells directed against the CD19 protein for the treatment of acute lymphoblastic leukemi...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Salas-Mckee, January, Kong, Weimin, Gladney, Whitney L., Jadlowsky, Julie K., Plesa, Gabriela, Davis, Megan M., Fraietta, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605860/
https://ncbi.nlm.nih.gov/pubmed/30735463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1571893
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