Patronin-mediated minus end growth is required for dendritic microtubule polarity

Microtubule minus ends are thought to be stable in cells. Surprisingly, in Drosophila and zebrafish neurons, we observed persistent minus end growth, with runs lasting over 10 min. In Drosophila, extended minus end growth depended on Patronin, and Patronin reduction disrupted dendritic minus-end-out...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Feng, Chengye, Thyagarajan, Pankajam, Shorey, Matthew, Seebold, Dylan Y., Weiner, Alexis T., Albertson, Richard M., Rao, Kavitha S., Sagasti, Alvaro, Goetschius, Daniel J., Rolls, Melissa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605808/
https://ncbi.nlm.nih.gov/pubmed/31076454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810155
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