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Detection of a novel panel of somatic mutations in plasma cell-free DNA and its diagnostic value in hepatocellular carcinoma

Background/aims: Circulating cell-free DNA (cfDNA) contains tumor-specific alterations and could potentially serve as “liquid biopsy”. The study was to identify a novel panel of hepatocellular carcinoma (HCC)-specific mutations in plasma cfDNA and to assess its value in the diagnosis of HCC. Materia...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Xiong, Yu, Xie, Cheng-Rong, Zhang, Sheng, Chen, Jin, Yin, Zhen-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605764/
https://ncbi.nlm.nih.gov/pubmed/31303788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S197455
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