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HDAC2 Selectively Regulates FOXO3a-Mediated Gene Transcription during Oxidative Stress-Induced Neuronal Cell Death

All neurodegenerative diseases are associated with oxidative stress-induced neuronal death. Forkhead box O3a (FOXO3a) is a key transcription factor involved in neuronal apoptosis. However, how FOXO3a forms complexes and functions in oxidative stress processing remains largely unknown. In the present...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Peng, Shengyi, Zhao, Siqi, Yan, Feng, Cheng, Jinbo, Huang, Li, Chen, Hong, Liu, Qingsong, Ji, Xunming, Yuan, Zengqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605534/
https://ncbi.nlm.nih.gov/pubmed/25609639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2444-14.2015
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