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Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex

Neuropathic pain is a debilitating condition for which the development of effective treatments has been limited by an incomplete understanding of its molecular basis. The cationic current I(h) mediated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels plays an important role in p...

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Vydáno v:J Neurosci
Hlavní autoři: Cordeiro Matos, Steven, Zhang, Zizhen, Séguéla, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605438/
https://ncbi.nlm.nih.gov/pubmed/26400952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0799-15.2015
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